STREPTOKINASE ALLELES AND DISEASE ASSOCIATION IN GROUP-A STREPTOCOCCI

Authors
HAASE A MELDER A KEMP D MATHEWS J
Citation
A. Haase et al., STREPTOKINASE ALLELES AND DISEASE ASSOCIATION IN GROUP-A STREPTOCOCCI, FEMS immunology and medical microbiology, 10(1), 1994, pp. 75-80
Citations number
22
Categorie Soggetti
Immunology,Microbiology
Journal title
FEMS immunology and medical microbiology → ACNP
ISSN journal
09288244
Volume
10
Issue
1
Year of publication
1994
Pages
75 - 80
Database
ISI
SICI code
0928-8244(1994)10:1<75:SAADAI>2.0.ZU;2-P
Abstract
Allele-specific oligonucleotides were used for PCR-based typing of the streptokinase locus of group A streptococcal strains, including well characterized type strains, isolates from patients with acute poststre ptococcal glomerulonephritis and strains from Aboriginal communities i n the Northern Territory of Australia. The streptokinase SKN allele, p reviously thought to be associated with glomerulonephritis, was no mor e frequent in nephritogenic than in non-nephritogenic streptococcal st rains in this collection.