PORTABLE, HIGH-BANDWIDTH FREQUENCY-DOMAIN PHOTON MIGRATION INSTRUMENTFOR TISSUE SPECTROSCOPY

Authors
MADSEN SJ ANDERSON ER HASKELL RC TROMBERG BJ
Citation
Sj. Madsen et al., PORTABLE, HIGH-BANDWIDTH FREQUENCY-DOMAIN PHOTON MIGRATION INSTRUMENTFOR TISSUE SPECTROSCOPY, Optics letters, 19(23), 1994, pp. 1934-1936
Citations number
10
Categorie Soggetti
Optics
Journal title
Optics letters → ACNP
ISSN journal
01469592
Volume
19
Issue
23
Year of publication
1994
Pages
1934 - 1936
Database
ISI
SICI code
0146-9592(1994)19:23<1934:PHFPMI>2.0.ZU;2-8
Abstract
We describe a novel frequency-domain photon migration instrument emplo ying direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical propertie s of biological tissues in near real time. An infinite medium diffusio n model was used to extract absorption and transport scattering coeffi cients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed t o within 10% of those expected.