ACETYLCHOLINESTERASE BASED AMPEROMETRIC SENSOR - INHIBITOR DETECTION

On the basis of the process of the acetylthiocholine iodide hydrolysis . catalysed by the enzyme inesterase and the obtaining of an electroac tive product, an amperometric sensor is created. Art electrochemically modified graphite electrode is used, with covalently linked directly on its surface acetylcholinesterase. It is demonstrated that it can be applied to the quantitative determination of some acetylcholinesteras e inhibitors insecticides and pharmaceuticals and for establishing the ir influence on the acetylcholinesterase activity.