K. Sandman et al., HISTONE-ENCODING GENES FROM PYROCOCCUS - EVIDENCE FOR MEMBERS OF THE HMF FAMILY OF ARCHAEAL HISTONES IN A NON-METHANOGENIC ARCHAEON, Gene, 150(1), 1994, pp. 207-208
Two genes, designated hpyA1 and hpyA2, have been cloned and sequenced
from Pyrococcus strain GB-3a. They are predicted to encode proteins (H
PyA1 and HPyA2, respectively) that are approx. 60% identical to the hi
stones HMf and HMt, characterized from methanogenic Archaea. These arc
haeal histones also contain the amino-acid sequences, conserved in euk
aryotic H4 histones, that are thought to interact directly with DNA.