PREVALENCE IN CRYPTOCOCCUS-NEOFORMANS STRAINS OF A POLYSACCHARIDE EPITOPE WHICH CAN ELICIT PROTECTIVE ANTIBODIES

Authors
CLEARE W MUKHERJEE S SPITZER ED CASADEVALL A
Citation
W. Cleare et al., PREVALENCE IN CRYPTOCOCCUS-NEOFORMANS STRAINS OF A POLYSACCHARIDE EPITOPE WHICH CAN ELICIT PROTECTIVE ANTIBODIES, Clinical and diagnostic laboratory immunology, 1(6), 1994, pp. 737-740
Citations number
30
Categorie Soggetti
Immunology,"Infectious Diseases","Medical Laboratory Technology",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
1
Issue
6
Year of publication
1994
Pages
737 - 740
Database
ISI
SICI code
1071-412X(1994)1:6<737:PICSOA>2.0.ZU;2-2
Abstract
Monoclonal antibody (MAb) 2H1 binds to an epitope in the capsule of Cr yptococcus neoformans that can elicit protective antibodies. The bindi ng of MAb 2H1 to C. neoformans strains was studied by agglutination, i mmunofluorescence, and phagocytosis assays. The MAb 2H1 epitope was pr esent in all 21 isolates studied, including those recovered from patie nts with recurrent infections.