Le. Rikans et al., AGE AND GENDER DIFFERENCES IN HEPATIC ASCORBIC-ACID CONCENTRATIONS AND NADPH-DEHYDROASCORBIC ACID REDUCTASE-ACTIVITY, Mechanism of ageing and development, 91(3), 1996, pp. 165-169
Ascorbic acid content decreased with age in livers of male rats but no
t in those of female rats. The influence of aging on the regeneration
of ascorbic acid from dehydroascorbic acid was investigated as a possi
ble cause of declining ascorbate concentrations. The results demonstra
te that hepatic NADPH-dehydroascorbic acid reductase activity is unaff
ected by aging.