Experiments are described demonstrating that experimental insemination
with autologous or homologous sperm into the ventral prostate or blad
der neck of outbred Zbar male rats induces intravesical precipitation
or stones. These observations suggest that clinical conditions resulti
ng in intravesical sperm may be contributory to bladder lithiasis in m
an and may have relevance to its prevalence in men vs. women.