DETERMINATION OF N-OCTANOL WATER PARTITION-COEFFICIENTS OF TETRACHLOROBENZYLTOLUENES INDIVIDUALLY AND IN A MIXTURE BY THE SLOW STIRRING METHOD

Experimentally obtained n-octanol/water partition coefficients (K-ow) are presented for nine TCBT isomers individually and in an eight isome rs mixture. The K-ow values were determined with the slow stirring met hod, which can provide K-ow values for very hydrophobic compounds. The log K-ow values of isomers determined individually ranged from 6.725 to 7.538 with standard deviations between 0.089 and 0.356. The log Kow values of TCBTs determined in the mixture ranged from 6.030 to 6.435 with standard deviations between 0.083 and 0.334. Reproducibility, iso mer resolution and differences between mixture and individual measurem ents are discussed.