EFFECT OF SESAMIN ON CHOLESTEROL-SYNTHESIS AND ON THE DISTRIBUTION OFINCORPORATED LINOLEIC-ACID IN LIPID SUBFRACTIONS IN CULTURED RAT-CELLS

Authors
UMEDASAWADA R FUJIWARA Y IGARASHI O
Citation
R. Umedasawada et al., EFFECT OF SESAMIN ON CHOLESTEROL-SYNTHESIS AND ON THE DISTRIBUTION OFINCORPORATED LINOLEIC-ACID IN LIPID SUBFRACTIONS IN CULTURED RAT-CELLS, Bioscience, biotechnology, and biochemistry, 58(11), 1994, pp. 2114-2115
Citations number
16
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
58
Issue
11
Year of publication
1994
Pages
2114 - 2115
Database
ISI
SICI code
0916-8451(1994)58:11<2114:EOSOCA>2.0.ZU;2-P
Abstract
Since sesamin influences the metabolism of essential fatty acids, its effects on cholesterol metabolism and on the incorporation of linoleic acid were studied by using cultured rat artery smooth muscle cells (S MCs) and primary cultured rat hepatocytes. Cholesterol synthesis from acetate was inhibited by sesamin in SMCs, and the distribution of inco rporated linoleic acid in the lipid and phospholipid subfractions was altered by sesamin in rat hepatocytes.