TEMPORAL-LOBE ABNORMALITIES IN MULTIGENERATIONAL FAMILIES WITH SCHIZOPHRENIA

Authors
HONER WG BASSETT AS SMITH GN LAPOINTE JS FALKAI P
Citation
Wg. Honer et al., TEMPORAL-LOBE ABNORMALITIES IN MULTIGENERATIONAL FAMILIES WITH SCHIZOPHRENIA, Biological psychiatry, 36(11), 1994, pp. 737-743
Citations number
30
Categorie Soggetti
Psychiatry
Journal title
Biological psychiatry → ACNP
ISSN journal
00063223
Volume
36
Issue
11
Year of publication
1994
Pages
737 - 743
Database
ISI
SICI code
0006-3223(1994)36:11<737:TAIMFW>2.0.ZU;2-R
Abstract
Brain structure in familial schizophrenia was studied with computerize d tomography in 42 individuals from six multigenerational families. Su lcal enlargement in the lateral temporal cortex, and ventricular and c isternal enlargement in the medial temporal region were observed in ps ychotic individuals compared to unaffected family members. Genetic fac tors in familial schizophrenia may exert part of their effect through determining or altering temporal lobe structure.