BACKGROUND: Cystic duct leak (CDL) appears to complicate laparoscopic
cholecystectomy (LC) more often than open cholecystectomy (OC). No men
tion of CDL was found in a literature review that covered 48,822 OCs a
nd their complications. PATIENTS AND METHODS: Fifty-four patients who
developed biliary tract injuries following LC were reviewed for: the t
ime from LC to presentation, presenting symptoms, method of diagnosis,
treatment, outcome, and follow-up. RESULTS: Seventeen of 54 biliary t
ract complications (31%) were CDLs. The CDLs presented at a median of
4 days after LC with pain (16%) and nausea and/or vomiting (35%). Endo
scopic retrograde cholangiopancreatography (ERCP) defined the diagnosi
s and the anatomy of the leak in 11 patients (65%). Biliary endoprosth
esis placement was employed in 8 patients, with concomitant sphinctero
tomy in 5 (63%), and resolved CDL in every case. Seven (88%) of these
patients were asymptomatic at a median interval of 10 months after ste
nt retrieval. Six patients (35%) underwent reoperation. Five had lapar
otomy with ligation of the cystic duet stump and 1 underwent laparosco
pic examination with reclipping of the cystic duct stump. Five (83%) w
ere asymptomatic at a median follow-up of 26 months. CDLs may result f
rom inaccurate clip placement, perforations proximal to the clips, and
stump necrosis, as documented at reoperation. CONCLUSIONS: CDLs occur
more frequently in LC than in the OCs reported in the literature. Mos
t leaks require intervention. ERCP with stent placement is the diagnos
tic and therapeutic procedure of choice and has a high success rate of
resolving leaks. To forestall CDLs, it is important to place clips ac
curately and avoid electrocautery in the vicinity of the cystic duct.