BACKGROUND: Although duodenal rupture is usually diagnosed during the
course of surgery for other injuries, a small portion of such injuries
occur in isolation. In such cases, the significance of the clinical a
nd dignostic findings may not be appreciated for an extended period. T
he primary determinant of mortality in duodenal rupture is the presenc
e of associated injuries, but delay in diagnosis is often a secondary
factor. METHODS: A retrospective case review of 8 patients with isolat
ed duodenal rupture that was diagnosed more than 24 hours following th
e injury. RESULTS: In 5 cases, physicians did not look for the occult
injury. In 3, patients did not seek medical attention. Two patients we
re initially treated with primary duodenal repair and drainage with po
or results. Ah patients were eventually treated with pyloric exclusion
that resulted in no deaths and no duodenal fistulas. Three patients d
eveloped abscesses after pyloric exclusion. They were drained without
difficulty. CONCLUSION: Pyloric exclusion appears to offer a satisfact
ory option for dealing with the inflammation and contamination that re
sult from prolonged soilage by duodenal contents.