H. Abe et al., COMPARISON OF TC-99M PERTECHNETATE WITH TL-201 AND GA-67 SCINTIGRAPHYOF MALIGNANT SOFT-TISSUE TUMORS, Clinical nuclear medicine, 22(1), 1997, pp. 38-41
Tc-99m pertechnetate scintigraphy was compared with Tl-201 chloride an
d Ga-67 citrate to evaluate the avidity of Tc-99m pertechtate for mali
gnant soft-tissue tumors. Twenty-three patients with malignant soft-ti
ssue tumors underwent scintigraphic studies. All 23 received Tc-99m an
d Tl-201, whereas 14 also were injected with Ga-67. In 21 (91%) of the
23 patients, Tc-99m accumulated extensively in the tumors. Tl-201 acc
umulated in 12 (52%) of the 23 tumors. Ga-67 accumulated in only 5 (36
%) of the 14 tumors. The avidity of Tc-99m for myxoid tumors was marke
dly different from the other two agents. Tc-99m accumulated in all eig
ht myxoid tumors, while neither Tl-201 or Ga-67 showed marked accumula
tion except for one patient with increased accumulation of Tl-201. Thi
s study shows that Tc-99m pertechnetate has the potential to localize
malignant soft-tissue tumors and may be useful in the evaluation of th
ese tumors.