Marker Assisted Selection (MAS) based on additive effects associated w
ith alleles at marker loci, estimated by linear regression of individu
al phenotype on the markers, was applied to characters with non-additi
ve gene action and non-additive environment. The base population was t
he F-2 generation of a cross between two inbred lines. Computer simula
tions of MAS were conducted for characters with dominance, epistasis a
nd genotype-environment interaction approximated by the 'additive-mult
iplicative' model. MAS was more effective than purely phenotypic selec
tion in all cases. The efficiency of MAS for characters with non-addit
ive gene action is comparable to (and for negative dominance even high
er than) the efficiency of MAS for strictly additive characters. Envir
onmental non-additivity, however, lowers the efficiency of MAS. Almost
all results concerning the efficiency of MAS in our previous simulati
ons of purely additive traits are applicable to non-additive traits.