Gluteal compartment syndrome is a rare disorder that most often occurs
in conjunction with prolonged immobility after a sedative overdose bu
t also may result from direct trauma. Patients present with localized
tenderness, induration, and pain with passive flexion of the gluteal m
uscles. Signs of sciatic nerve compression occur frequently, and rhabd
omyolysis may be associated with the syndrome. If the diagnosis of glu
teal compartment syndrome is suspected, intracompartmental pressures s
hould be measured. If pressures are high or if sufficient clinical sus
picion remains, the patient should undergo prompt fasciotomy.