Ac. Johnstone et al., PAPILLOMAVIRUS-INDUCED DERMATOFIBROMA IN CATTLE FOLLOWING TUBERCULIN TESTING, New Zealand Veterinary Journal, 42(6), 1994, pp. 233-235
Papillomavirus was identified in two fibromatous dermal nodules which
were representative of those present in the caudal fold skin of the ta
il in 25 of 145 beef cattle tuberculin tested 3 months earlier. Bovine
warts were endemic on the property and it is hypothesised that the pa
pilloma virus was introduced intradermally by a virus-contaminated tub
erculin syringe. At palpation, the well-circumscribed hard nodular les
ions were atypical of the diffuse caudal fold swelling usually present
in reactions to tuberculin. Provided tuberculin testing officers are
aware of the risk of fibroma and papilloma induction by transmission o
f papillomavirus, and they are careful to prevent equipment coming int
o contact with warts at time of inoculation, this source of inaccuracy
may be avoided.