Objective/Design: A randomized double-blind controlled study was condu
cted on two groups of 45 parturients to evaluate the importance of the
timing of epidural morphine administration for the relief of postepis
iotomy pain. Both groups had preemptive analgesia by continuous lumbar
epidural bupivacaine blockade. Upon completion of the episiotomy repa
ir and before the onset of pain, the patients received epidural inject
ions of 3 ml saline with or without 2 mg morphine in groups A and B re
spectively. When pain appeared, group A patients received an epidural
injection of 3 ml saline while group B patients received 2 mg morphine
in 3 ml saline. Postepisiotomy pain level was evaluated by a visual a
nalogue scale. Results: The incidence of pain in group B women followi
ng epidural morphine administration was 68.6%. This was significantly
higher than that of group A at 15.6% (p < 0.01). Furthermore, group B
showed that the rate of effective pain relief after 2 mg epidural morp
hine significantly decreases as the level of pain intensity rises (p <
0.01). Conclusion: Epidural morphine for postepisiotomy pain is much
more effective if administered before the onset of pain.