PRODRUGS OF ANALOGS OF NUCLEIC-ACID COMPONENTS

Authors
ALEXANDER P HOLY A
Citation
P. Alexander et A. Holy, PRODRUGS OF ANALOGS OF NUCLEIC-ACID COMPONENTS, Collection of Czechoslovak Chemical Communications, 59(10), 1994, pp. 2127-2165
Citations number
221
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
59
Issue
10
Year of publication
1994
Pages
2127 - 2165
Database
ISI
SICI code
0010-0765(1994)59:10<2127:POAONC>2.0.ZU;2-X
Abstract
This review regards various attitudes to the rational design of prodru gs derived of nucleoside and nucleotide analogues with pronounced biol ogical (antiviral, anticancer) activity. Particular attention is focus ed on the recent development of prodrugs of approved therapeutic agent s with the above structural association.