MIGRATION OF NEURONS CONTAINING GONADOTROPIN-RELEASING-HORMONE (GNRH)IN SLICES FROM EMBRYONIC NASAL COMPARTMENT AND FOREBRAIN

Citation
Sa. Tobet et al., MIGRATION OF NEURONS CONTAINING GONADOTROPIN-RELEASING-HORMONE (GNRH)IN SLICES FROM EMBRYONIC NASAL COMPARTMENT AND FOREBRAIN, Developmental brain research, 97(2), 1996, pp. 287-292
Citations number
25
Categorie Soggetti
Neurosciences
ISSN journal
01653806
Volume
97
Issue
2
Year of publication
1996
Pages
287 - 292
Database
ISI
SICI code
0165-3806(1996)97:2<287:MONCG(>2.0.ZU;2-O
Abstract
During development, neurons containing gonadotropin-releasing hormone traverse fiber bundles in the nose, cross into the brain, and move thr ough a maze of glial and axonal fibers. To test whether GnRH neurons u tilize cues intrinsic to their migration route to traverse the nasal/b rain boundary, tissue slices that maintain connections between the for ebrain and nasal compartment were prepared from mouse embryos. Cell mi gration between the nasal and brain compartments was evident based on changes in cell positions after successive days in vitro.