Yh. Zhu et al., NONPENETRATING, ARCUATE-LEGGED CLIP RECONSTRUCTION OF THE RAT UTERINEHORN, The Journal of the American Association of Gynecologic Laparoscopists, 1(4), 1994, pp. 395-400
A new method for reconstructing rat uterine horn was developed in whic
h nonpenetrating, arcuate-legged clips are applied in interrupted fash
ion to everted seromuscular edges, forming an elastomeric flanged join
t. This anastomosis has unusual physical and morphologic properties, w
ith improved tissue healing and luminal restitution. Clipping is easie
r than suturing, and resulted in equivalent fertility rate (50-60%) an
d litter size. II also is associated with less granuloma formation and
hystiocytic infiltration than suture. The new technique has the poten
tial of endoscopic translation for human tubal reconstruction.