J. Hatter et al., PREOPERATIVE EVALUATION OF STAGE-I AND STAGE-II NONSMALL CELL LUNG-CANCER, The Annals of thoracic surgery, 58(6), 1994, pp. 1738-1741
The appropriate preoperative evaluation for occult metastasis in patie
nts with potentially resectable lung cancer remains controversial. The
records of 265 patients with stage I and II non-small cell lung cance
rs who underwent resection with curative intent were reviewed to deter
mine if there was a survival benefit of negative preoperative scanning
to detect metastases. A minimum of 5 years of follow-up was possible
for all long-term survivors. Patients having preoperative bone scans,
brain imaging, and abdominal imaging had no increased survival over th
ose without such evaluation (using Kaplan-Meier survival curves). Addi
tionally, no difference was found in the time to first recurrence betw
een these groups, and the site of recurrence was independent of a nega
tive preoperative scan for that location. These data, using patient ou
tcome as the basis of our conclusion, support a policy of reserving ex
pensive preoperative metastatic evaluations only for those patients wi
th clinical evidence of metastatic disease.