REGULATORY MECHANISMS THAT COORDINATE SKELETAL-MUSCLE DIFFERENTIATIONAND CELL-CYCLE WITHDRAWAL

Authors
LASSAR AB SKAPEK SX NOVITCH B
Citation
Ab. Lassar et al., REGULATORY MECHANISMS THAT COORDINATE SKELETAL-MUSCLE DIFFERENTIATIONAND CELL-CYCLE WITHDRAWAL, Current opinion in cell biology, 6(6), 1994, pp. 788-794
Citations number
55
Categorie Soggetti
Cytology & Histology
Journal title
Current opinion in cell biology → ACNP
ISSN journal
09550674
Volume
6
Issue
6
Year of publication
1994
Pages
788 - 794
Database
ISI
SICI code
0955-0674(1994)6:6<788:RMTCSD>2.0.ZU;2-F
Abstract
Skeletal muscle differentiation entails the coupling of muscle-specifi c gene expression to terminal withdrawal from the cell cycle. Several models have recently been proposed which attempt to explain how regula ted expression and function of myogenic transcription factors ensures that proliferation and differentiation of skeletal muscle cells are mu tually exclusive processes.