ALDOL-TYPE REACTION OF ALPHA-HALO KETONES WITH ALPHA-KETOCARBOXYLATESMEDIATED BY SML(2) OR SML(3) - FACILE SYNTHESIS OF ALPHA-HYDROXY-GAMMA-KETOCARBOXYLATES

Authors
ARIME T KATO N KOMADATE F SAEGUSA H MORI N
Citation
T. Arime et al., ALDOL-TYPE REACTION OF ALPHA-HALO KETONES WITH ALPHA-KETOCARBOXYLATESMEDIATED BY SML(2) OR SML(3) - FACILE SYNTHESIS OF ALPHA-HYDROXY-GAMMA-KETOCARBOXYLATES, Synthetic communications, 24(22), 1994, pp. 3315-3319
Citations number
3
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
24
Issue
22
Year of publication
1994
Pages
3315 - 3319
Database
ISI
SICI code
0039-7911(1994)24:22<3315:AROAKW>2.0.ZU;2-L
Abstract
The title reaction smoothly proceeds at room temperature to give alpha -hydroxy-gamma-keto esters 3 in good yields, probably via a mechanism involving samarium enolates formed in situ from alpha-halo ketones.