TARDIVE DYSTONIA - A RARE SIDE-EFFECT IND UCED BY NEUROLEPTICS

Citation
Hj. Assion et F. Heinemann, TARDIVE DYSTONIA - A RARE SIDE-EFFECT IND UCED BY NEUROLEPTICS, Nervenarzt, 65(11), 1994, pp. 795-797
Citations number
20
Categorie Soggetti
Psychiatry,Neurosciences
Journal title
ISSN journal
00282804
Volume
65
Issue
11
Year of publication
1994
Pages
795 - 797
Database
ISI
SICI code
0028-2804(1994)65:11<795:TD-ARS>2.0.ZU;2-V
Abstract
This paper reports on a case of spasmodic torticollis after long-term treatment with neuroleptics. This form of dystonia is called tardive d ystonia to distinguish it from tardive dyskinesia. Its pathophysiology is unknown. Pathological changes are described in the basal ganglia. Increased signal was found on magnetic resonance imaging on both sides of the basal ganglia reflecting structural lesions. These structural changes, together with neuroleptic medication, represent predisposing factors for the manifestation of tardive dystonia.