A self-setting apatite cement, EBA cement, and amalgam with varnish we
re tested for root end sealing ability using a fluid filtration and dy
e technique. Single-rooted human teeth were prepared in vitro to recei
ve root end fillings. Experimental groups were amalgam with two layers
of varnish, EBA cement with dry cavity, EBA cement within a wet cavit
y, apatite cement within a dry cavity, and apatite cement within a wet
cavity. Fluid filtration measurements were made at 6, 24, and 7 days,
and 1 and 3 months. Each specimen was also subjected to a dye leakage
test using Procion Green dye at 3 months. Results indicated that apat
ite cement provided a comparable seal to amalgam and EBA cement. This
finding, in conjunction with its excellent biocompatibility, suggests
that apatite cement is an acceptable alternative to present-day root e
nd filling materials.