This article summarizes published data on employment and cancer patter
ns in the motor vehicle manufacturing (MVM) industry and presents resu
lts from a new study of female MVM workers. Historically, female MVM e
mployees worked primarily in aerospace; electric and electronic equipm
ent manufacturing; and paint, plastic, and trim operations. Women are
now moving into vehicle assembly and metal parts production. Investiga
tions of cancer have focused on men and reported excesses of lung canc
er in foundry operations, of gastrointestinal cancer in metal processi
ng operations involving exposure to machining fluids, and of colorecta
l cancer in wood pattern making. Numbers of women were insufficient fo
r a meaningful evaluation of their cancer patterns. A recent study fou
nd that white women employed at a MVM company, compared to the female
general US population, had small excesses of lung cancer (standardized
mortality ratio (SMR) = 1.26; 95% confidence interval (CI) = 0.96-1.6
3) and of colorectal cancer (SMR = 1.27, 95% CI = 0.87-1.78) and a def
icit of breast cancer (SMR = 0.68, 95% CI = 0.48-0.92). The lung cance
r increase was concentrated among women in assembly jobs (SMR = 1.58,
95% CI = 1.07-2.26); the colorectal cancer increase, among women in no
nproduction jobs (SMR = 1.78, 95% CI = 0.97-2.98); and the breast canc
er deficit, among women in production-related jobs (SMR = 0.60, 95% CI
= 0.37-0.91). Further investigation is needed to determine if these p
atterns are due to the occupational environment and to clarify causes
of cancer among women in the MVM industry.