CENTROCYTIC-LIKE LYMPHOMA ASSOCIATED WITH LOCALIZED AMYLOIDOSIS OF THE LARGE-INTESTINE

Authors
RANALDI R GOTERI G SANTINELLI A REZAI B PILERI S POGGI S BEARZI I
Citation
R. Ranaldi et al., CENTROCYTIC-LIKE LYMPHOMA ASSOCIATED WITH LOCALIZED AMYLOIDOSIS OF THE LARGE-INTESTINE, Virchows Archiv, 425(3), 1994, pp. 327-330
Citations number
17
Categorie Soggetti
Pathology
Journal title
Virchows Archiv → ACNP
ISSN journal
09456317
Volume
425
Issue
3
Year of publication
1994
Pages
327 - 330
Database
ISI
SICI code
0945-6317(1994)425:3<327:CLAWLA>2.0.ZU;2-S
Abstract
A case of low-grade centrocytic-like (CCL) B-cell lymphoma involving t he large intestine, the regional lymph nodes and the spleen is reporte d. In the large in testine the lymphomatous infiltrate was restricted to sites of intense antigenic stimulation (diverticula, appendix, ileo -caecal valve) and was associated with marked plasma cell differentiat ion and massive amyloid deposits. The immunophenotype was CD20, CD21, CD45RA/MB1/MT2, CD68, CD45 related/Ki-B3 and HLA-DR positive, and MB2, DBA.44 reactive regarding the CCL cell lymphoma subpopulation; and Ig G-lambda positive regarding its plasma cell fraction.