The purpose of this study was to identify variables that are associate
d with noncompliance among adult renal transplant recipients, includin
g demographic characteristics, transplant-related variables, and psych
osocial factors. The measurement of noncompliance was improved by asse
ssing noncompliant behaviors (i.e., noncompliance with medications and
the follow-up regimen) prior to the onset of complications and/or gra
ft loss and by measuring compliance as a continuous rather than dichot
omous variable. Two-hundred-and-forty-one renal transplant recipients
completed the Beck Depression Inventory, the anxiety and hostility sub
scales of the Brief Symptom Inventory, the Multidimensional Health Loc
us of Control Scale, the Inventory of Socially Supportive Behaviors, t
he Coping Strategies Inventory, a measure of transplant-related stress
ors, and self-report measures of compliance with medications and the f
ollow-up regimen. Approximately half of our sample reported at least s
ome degree of noncompliance. Recipients who were younger, female, unma
rried, retransplanted, and with lower incomes tended to be noncomplian
t with medications (all p's<0.05). Recipients who were unmarried, low
income, not insulin-dependent, and with a longer time since transplant
tended to be noncompliant with the follow-up regimen. In addition, re
cipients who reported higher stress and more depression, who coped wit
h stress by using avoidant coping strategies, and who believed that he
alth outcomes are beyond their control were less compliant with both m
edications and follow-up (all p's<0.05). Regression analyses revealed
that stress was the strongest predictor of both medication and follow-
up compliance.