In clinical practice the presence of a positive family history of diab
etes mellitus is one of the criteria to perform a glucose screening te
st. However it has been shown not be always reliable. The aim of this
study is to verify the concordance between the data referred by a grou
p of daughters about the existence of diabetes mellitus in both parent
s, the data given by their parents, and a corroboration by blood gluco
se testing of the parents. A total of 82 triads (father, mother and da
ughter) were studied. The daughters were healthy and belonged to a coh
ort of perinatal studies of the Instituto Nacional de Perinatologia in
Mexico City; they were not pregnant and had both parents alive, who a
greed to participate in the study. Each daughter was asked about her p
arents history of diabetes having three options as an answer: yes, no,
do not know. The same information about themselves was asked to the p
arents separately, not giving a chance to the members of the triad to
communicate among themselves. The necessary glucose tests were perform
ed to integrate a diagnosis by accepted international criteria. A chi-
square test was used to compare the data referred by parents and daugh
ters; agreement percentage (kappa values) were calculated. A prespecif
ied order test was performed to the answers given and evaluated by occ
urrence rates (Bartholomew's test). In the latter analysis there were
significant differences (p < 0.001) between the answer given by the pa
rents, daughter and the confirmed blood glucose values. No differences
were found between what the parents said, nor in what they said and w
hat the daughters answered.