ANTIOXIDANT PROPERTIES OF DEHYDROZINGERONE AND CURCUMIN IN RAT-BRAIN HOMOGENATES

Authors
RAJAKUMAR DV RAO MNA
Citation
Dv. Rajakumar et Mna. Rao, ANTIOXIDANT PROPERTIES OF DEHYDROZINGERONE AND CURCUMIN IN RAT-BRAIN HOMOGENATES, Molecular and cellular biochemistry, 140(1), 1994, pp. 73-79
Citations number
40
Categorie Soggetti
Biology
Journal title
Molecular and cellular biochemistry → ACNP
ISSN journal
03008177
Volume
140
Issue
1
Year of publication
1994
Pages
73 - 79
Database
ISI
SICI code
0300-8177(1994)140:1<73:APODAC>2.0.ZU;2-I
Abstract
The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneou s lipid peroxidation. These compounds also inhibited lipid peroxidatio n induced by ferrous ions, ferric-ascorbate and ferric-ADP-ascorbate. In all these cases, curcumin was more active than dehydrozingerone and dl-alpha-tocopherol.