REGIOSELECTIVE IMIDE REDUCTION - AN ISSUE IN THE TOTAL SYNTHESIS OF STAUROSPORINE

Citation
Jt. Link et Sj. Danishefsky, REGIOSELECTIVE IMIDE REDUCTION - AN ISSUE IN THE TOTAL SYNTHESIS OF STAUROSPORINE, Tetrahedron letters, 35(49), 1994, pp. 9135-9138
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
35
Issue
49
Year of publication
1994
Pages
9135 - 9138
Database
ISI
SICI code
0040-4039(1994)35:49<9135:RIR-AI>2.0.ZU;2-K
Abstract
An imide was regioselectively reduced to either of its corresponding l actams. These lactams serve as potent glycosyl accepters and can be co nverted into the aglycone of staurosporine.