DESIGNED NUCLEOPHILIC-ATTACK BASED ON MOLECULAR ELECTROSTATIC POTENTIAL

Authors
KESERU GM KAJTARPEREDY M NARAYSZABO G
Citation
Gm. Keseru et al., DESIGNED NUCLEOPHILIC-ATTACK BASED ON MOLECULAR ELECTROSTATIC POTENTIAL, Tetrahedron letters, 35(49), 1994, pp. 9255-9258
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
49
Year of publication
1994
Pages
9255 - 9258
Database
ISI
SICI code
0040-4039(1994)35:49<9255:DNBOME>2.0.ZU;2-R
Abstract
We describe the computer-aided design of the steric preference in a nu cleophilic attack on sterically unbiased carbonyl groups. To our knowl edge, this is the first example for the successful application of the molecular electrostatic potential map to computer-assisted synthesis.