Kekulene, antikekulene and related structures are discussed in terms o
f the current aromaticity and reactivity indices. Kekulene is predicte
d to be aromatic and stable. This prediction is in agreement with expe
rimental findings. Antikekulene is predicted to be nonaromatic and rea
ctive. The synthesis of antikekulene has not yet been accomplished, bu
t it seems that its preparation is imminent. Nevertheless, our predict
ions indicate that the preparation of antikekulene is going to be diff
icult.