A convex polytope in real Euclidean space is lattice-free if it inters
ects some lattice in space exactly in its vertex set. Lattice-free pol
ytopes form a large and computationally hard class, and arise in many
combinatorial and algorithmic contexts. In this article, affine and co
mbinatorial properties of such polytopes are studied. First, bounds on
some invariants, such as the diameter and layer-number, are given. It
is shown that the diameter of a d-dimensional lattice-free polytope i
s O(d3). A bound of O(nd + d3) on the diameter of a d-polytope with n
facets is deduced for a large class of integer polytopes. Second, Dela
unay polytopes and [0, 1]-polytopes, which form major subclasses of la
ttice-free polytopes, are considered. It is shown that, up to affine e
quivalence, for any d greater-than-or-equal-to 3 there are infinitely
many d-dimensional lattice-free polytopes but only finitely many Delau
nay and [0, 1]-polytopes. Combinatorial-types of lattice-free polytope
s are discussed, and the inclusion relations among the sub-classes abo
ve are examined. It is shown that the classes of combinatorial-types o
f Delaunay polytopes and [0, 1]-polytopes are mutually incomparable st
arting in dimension six, and that both are strictly contained in the c
lass of combinatorial-types of all lattice-free polytopes.