1,5-DIAZACYCLOOCTANE-3,7-DERIVATIVES AS PRECURSORS OF THE 3,7-DIAZA[3.3.0]BICYCLOOCTANE AND 3,7,10-HETEROCYCLIC[3.3.3]PROPELLANE RING-SYSTEMS

Authors
DAVE PR FOROHAR F AXENROD T QI LD WATNICK C YAZDEKHASTI H
Citation
Pr. Dave et al., 1,5-DIAZACYCLOOCTANE-3,7-DERIVATIVES AS PRECURSORS OF THE 3,7-DIAZA[3.3.0]BICYCLOOCTANE AND 3,7,10-HETEROCYCLIC[3.3.3]PROPELLANE RING-SYSTEMS, Tetrahedron letters, 35(48), 1994, pp. 8965-8968
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
48
Year of publication
1994
Pages
8965 - 8968
Database
ISI
SICI code
0040-4039(1994)35:48<8965:1APOT3>2.0.ZU;2-C
Abstract
A simple synthesis of 3,7-disubstituted-1,5-diazacyclooctanes from p-t oluenesulfonamides and 3-chloro-2-chloromethylpropene has been develop ed. Unusual transannular reactions in these eight-membered ring interm ediates provide easy access to novel 3,7-diaza[3.3.0]bicyclooctane and 3,7,10-heterocyclic[3.3.3]propellane ring systems.