THE ALLYLOXYCARBONYLAMINOMETHYL GROUP - A NEW ALLYLIC PROTECTION FOR THE THIOL-GROUP OF CYSTEINE

Authors
KIMBONGUILA AM MERZOUK A GUIBE F LOFFET A
Citation
Am. Kimbonguila et al., THE ALLYLOXYCARBONYLAMINOMETHYL GROUP - A NEW ALLYLIC PROTECTION FOR THE THIOL-GROUP OF CYSTEINE, Tetrahedron letters, 35(48), 1994, pp. 9035-9038
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
48
Year of publication
1994
Pages
9035 - 9038
Database
ISI
SICI code
0040-4039(1994)35:48<9035:TAG-AN>2.0.ZU;2-5
Abstract
S-Allocam derivatives of thiols in general and of cysteine in particul ar are selectively and readily deprotected through palladium catalyzed hydrostanoolysis. They are perfectly stable in the basic conditions o f Fmoc-removal. but only marginally stable in the acidic conditions of t-Bu, Boc removal.