PER-6-BROMO-PER-2,3-DIMETHYL-BETA-CYCLODEXTRIN

Authors
ALKER D ASHTON PR HARDING VD KONIGER R STODDART JF WHITE AJP WILLIAMS DJ
Citation
D. Alker et al., PER-6-BROMO-PER-2,3-DIMETHYL-BETA-CYCLODEXTRIN, Tetrahedron letters, 35(48), 1994, pp. 9091-9094
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
48
Year of publication
1994
Pages
9091 - 9094
Database
ISI
SICI code
0040-4039(1994)35:48<9091:P>2.0.ZU;2-P
Abstract
An efficient synthesis of the title compound, per-6-bromo-per-2,3-dime thyl-beta-cyclodextrin, is described, giving access to a highly solubl e cyclodextrin, which may be used for further chemical modification of beta-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, reveal ing a cyclodextrin derivative whose conformation deviates substantiall y from C-7 symmetry.