COMBINED IMMUNOMODULATION (PROPIONIBACTERIUM-AVIDUM KP-40) AND LECTINBLOCKING (D-GALACTOSE) PREVENTS LIVER-TUMOR COLONIZATION IN BALB C-MICE/

Authors
PULVERER G KO HL TUNGGAL L BEUTH J JELJASZEWICZ J
Citation
G. Pulverer et al., COMBINED IMMUNOMODULATION (PROPIONIBACTERIUM-AVIDUM KP-40) AND LECTINBLOCKING (D-GALACTOSE) PREVENTS LIVER-TUMOR COLONIZATION IN BALB C-MICE/, Zentralblatt fur Bakteriologie, 281(4), 1994, pp. 491-494
Citations number
17
Categorie Soggetti
Microbiology,Virology
Journal title
Zentralblatt fur Bakteriologie → ACNP
ISSN journal
09348840
Volume
281
Issue
4
Year of publication
1994
Pages
491 - 494
Database
ISI
SICI code
0934-8840(1994)281:4<491:CI(KAL>2.0.ZU;2-1
Abstract
The protective effect of combined treatment (immunomodulation with Pro pionibacterium avidtim KP-40; liver lectin blocking by D-galactose adm inistration) on the liver colonization of RAW 117-H10 lymphosarcoma wa s investigated in BALB/c-mice. Both, immunomodulation with P. avidum K P-40 as well as liver lectin blocking by D-galactose treatment signifi cantly decreased the number of liver tumor colonies in this experiment al model. However, the combination of P. avidum KP-40 and D-galactose obviously proved to be superior to each monotherapy since the liver co lonization by RAW 117-H10 lymphosarcoma could be completely inhibited.