Rk. Hommel et al., EFFECT OF AMMONIUM-IONS ON GLYCOLIPID PRODUCTION BY CANDIDA (TORULOPSIS) APICOLA, Applied microbiology and biotechnology, 42(2-3), 1994, pp. 192-197
The effect of ammonium on growth of Candida apicola and on production
of sophorose lipid was studied. Sophorose lipid production increased w
ith increasing initial ammonium sulphate concentration. Both growth an
d product formation were strongly reduced at 73.6 mM ammonium. With 58
.9 mM ammonium a microcrystalline sophorose lipid was formed. The rati
o of the two isomers of the sophorose lipid, harbouring either omega-
or omega-1 hydroxy fatty acid, was influenced by the initial concentra
tion of ammonium. Both production kinetics, yields and profiles of the
total cellular fatty acids express alterations with enlarged ammonium
concentrations. These results suggest regulatory effects of ammonium
on C. apicola and its sophorose lipid synthesis.