BECKER MUSCULAR-DYSTROPHY WITH ONSET AFTER 60 YEARS

We report an unusual example of Becker muscular dystrophy in which the patient was asymptomatic until his mid-60s, and diagnosis was not mad e until he was 67 years old. The patient had the unusual deletion of e xons 3 to 9 within an actin-binding region of the dystrophin gene, rem oval or disruption of which is almost invariably associated with a mor e severe clinical phenotype. Our case illustrates the danger of drawin g conclusions about possibly symptomatic deletions without lifelong fo llow-up.