Bile leaks are the most common biliary complication of laparoscopic ch
olecystectomy. Cholescintigraphy has been utilized in the past to diag
nose postoperative bile leaks after open cholecystectomy. However, the
sensitivity and specificity of this imaging technique has not been de
fined or compared to other clinical tests. We have retrospectively stu
died 30 patients over a 2-yr period who underwent cholescintigraphy fo
r a possible postoperative bile leak. This study reviewed the cholesci
ntigraphy images, clinical presentations, and abdominal ultrasonograph
y/CT scanning. Using a gold standard that consisted of the findings of
cholangiography and clinical outcome, we determined the diagnostic ac
curacy of these tests. Symptoms, laboratory testing, and physical exam
ination were found to be poor predictors for the presence of postopera
tive bile leaks. Ultrasound and CT imaging were less sensitive and non
specific. In contrast, cholescintigraphy was found to be quite accurat
e (83-87%) for predicting the presence of bile leaks after laparoscopi
c cholecystectomy, as well as other biliary surgeries.