A COGNITIVE MODEL FOR SCHIZOPHRENIA AND ITS POSSIBLE NEURAL BASIS

It is proposed that the basic disturbance in schizophrenia corresponds to a disruption of the normal relationship between stored material an d current sensory input. The link between information processing distu rbances and their biological bases may be facilitated by the use of pa radigms derived from animal learning theory. A model for the emergence of schizophrenic symptoms is presented. The core cognitive abnormalit y may result from a disturbance at any point in the neural circuit inv olved in the prediction of subsequent sensory input.