Memory impairment in schizophrenia has been reported in several studie
s during the last decades. Issues related to the interpretation of suc
h deficits are discussed. Research strongly suggests specific memory d
ysfunction in schizophrenia that may be neither drug induced nor secon
dary consequences of attentional disorders. Our own longitudinal data
indicate that these deficits deviate from normal function in a relativ
ely stable way. Although medial temporal lobe structures seems to be o
f special importance, memory function may be vulnerable to a variety o
f neurobiological abnormalities.