Objective-To evaluate characteristics of patients and accessory pathwa
ys as well as additional technical factors involved in the reappearanc
e of accessory pathway conduction after successful ablation. Design-An
alysis of recurrences after radiofrequency ablation. Setting-163 conse
cutive patients with 167 accessory pathways. Subjects-97 men and 66 wo
men with a mean (SD) age of 36 (14) range (11 to 75) years. Results-Af
ter a mean (SD) follow up of 14 (7) range (2 to 27) months, conduction
recurred in 13 out of 167 (7.8%) accessory pathways. The initial mani
festation of recurrence was circus movement tachycardia in 7 patients
and reappearance of delta waves on a 12 lead electrocardiogram in 6 pa
tients. The interval to the return of accessory pathway conduction ran
ged from 3 hours to 90 days. Age, sex, presence of multiple accessory
pathways, criteria to determine the target ablation site, number and d
uration of radiofrequency applications, and cumulative energy did not
significantly differ between the groups with recurrence and without. R
ecurrence was less common with concealed accessory pathways (2/44) tha
n with overt accessory pathways (11/110). The difference was not signi
ficant. The only variable to influence the recurrences in this study g
roup was the location of the accessory pathway. Reappearance of conduc
tion through right sided accessory pathways occurred significantly mor
e often than through left sided ones (8/40 v 5/114, P = 0.01). Conclus
ion-After radiofrequency ablation the recurrence rate of accessory pat
hways is low and there are no predictors of the risk of reappearance o
f conduction apart from the right sided location of the accessory path
way.