Objective: To reassess the therapeutic options for pancreatic pseudocy
sts, resulting from the refinement of imaging techniques of the pancre
as over the past 15 years. Data Sources: An extensive review of the li
terature for the period 1970 to 1994. When pertinent, the authors' exp
erience with 45 patients was added to the literature data. Study Crite
ria: In the literature review the following selection criteria were us
ed: diagnostic modalities (clinical, endoscopic and radiologic); clini
cal context (etiology and clinical presentation); and therapeutic moda
lities (observation and drainage). Data Extraction and Synthesis: Data
collection was retrospective in most series. Whenever possible data c
ollected before 1980 were differentiated from those collected after 19
80 because diagnostic modalities were quite different in these two per
iods. Conclusions: Pancreatic pseudocysts are now diagnosed with more
certainty and followed with more precision. Long-term observation is a
safe and valuable approach. In symptomatic patients, some form of dra
inage should be considered. In an elective situation, internal drainag
e (endoscopic or surgical) is favoured. Cystogastrostomy should not be
associated with an increased risk of bleeding.