PATTERNS OF ANTIBODIES TO HEPATITIS-C VIRUS AND HEPATITIS-C VIRUS-REPLICATION IN CHILDREN WITH CHRONIC NON-A, NON-B-HEPATITIS

Authors
BORTOLOTTI F VAJRO P BARBERA C CRIVELLARO C ZANCAN L GIACCHINO R NEBBIA G LEPORE L BARBIERATO E DEMOLINER L CAVALLETTO D ALBERTI A
Citation
F. Bortolotti et al., PATTERNS OF ANTIBODIES TO HEPATITIS-C VIRUS AND HEPATITIS-C VIRUS-REPLICATION IN CHILDREN WITH CHRONIC NON-A, NON-B-HEPATITIS, The Journal of pediatrics, 125(6), 1994, pp. 916-918
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
125
Issue
6
Year of publication
1994
Part
1
Pages
916 - 918
Database
ISI
SICI code
0022-3476(1994)125:6<916:POATHV>2.0.ZU;2-6
Abstract
Antibodies to hepatitis C virus (HCV), investigated by second- and thi rd-generation assays, were detected in 74% of 43 children with chronic non-A, non-B hepatitis, The polymerase chain reaction identified HCV ribonucleic acid in 26 (93%) of 28 seropositive and in 1 of 10 seroneg ative cases. Intermittent HCV ribonucleic acid positivity, suggesting low and fluctuating viremia, was frequent in younger patients,