A systematic mathematical framework for scheduling the operation of mu
ltipurpose batch/semicontinuous plants involving heat-integrated unit
operations is presented. The approach advocated takes direct account o
f the trade-offs between maximal exploitation of heat integration and
other scheduling objectives and constraints. Both direct and indirect
heat integration are considered. In the former case, heat transfer tak
es place directly between the fluids undergoing processing in the heat
-integrated unit operations, and therefore a degree of time overlap of
these operations must be ensured. It is shown that this involves only
relatively minor modifications to existing detailed scheduling formul
ations. Indirect heat integration utilizes a heat transfer medium (HTM
) which acts as a mechanism both for transferring heat from one operat
ion to another and for storing energy over time. This provides a degre
e of decoupling with respect to the timing of the operations involved.
The mathematical formulation presented in this paper is based on a de
tailed characterization of the variation of the mass and energy holdup
s of HTM over time. In particular, it takes account of the limitations
on energy storage due to heat losses to the environment. A modified b
ranch-and-bound procedure is proposed for the solution of the resultin
g nonconvex mixed integer nonlinear programming problem.