METABOLISM OF THE POLYCYCLIC AROMATIC HYDROCARBON PYRENE BY ASPERGILLUS-NIGER SK-9317

Authors
WUNDER T KREMER S STERNER O ANKE H
Citation
T. Wunder et al., METABOLISM OF THE POLYCYCLIC AROMATIC HYDROCARBON PYRENE BY ASPERGILLUS-NIGER SK-9317, Applied microbiology and biotechnology, 42(4), 1994, pp. 636-641
Citations number
21
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Applied microbiology and biotechnology → ACNP
ISSN journal
01757598
Volume
42
Issue
4
Year of publication
1994
Pages
636 - 641
Database
ISI
SICI code
0175-7598(1994)42:4<636:MOTPAH>2.0.ZU;2-2
Abstract
The metabolism of pyrene, a polycyclic aromatic hydrocarbon consisting of four rings, by Aspergillus niger SK 9317 was investigated. The met abolites formed were isolated and identified as 1-hydroxypyrene. 1,6- and 1,8-pyrenequinone, 1,6- and 1,8-dihydroxypyrene, 1-pyrenyl sulphat e and 1-hydroxy-8-pyrenyl sulphate. This is the first report of 1-hydr oxy-8-pyrenyl as a metabolite in the microbial metabolism of pyrene. T he results suggest that A. niger metabolizes pyrene by cytochrome P-45 0 monooxygenase enzyme systems.