The evolution of a naevus spilus is documented with serial photographs
over a 12-year period, The lesion was remarkable for increasing numbe
rs of macules and papules within the background of the cafe-au-lait ma
cule, Biopsy of a new papule showed lentiginous melanocytic hyperplasi
a without atypia, We advise photography and periodic follow-up of larg
e, clinically atypical or changing naevi spill. Indications for consid
ering biopsy of naevi spill, irrespective of size, include atypical cl
inical features or change in one of the hyperpigmented macules or papu
les, eventuating in an atypical clinical appearance.