EFFECT OF RETINOIC ACID ON CONTRACTION OF COLLAGEN GEL INDUCED BY FIBROBLASTS

Authors
LEW HS TSUCHIHASHI M TENSHIN S KAWATA T
Citation
Hs. Lew et al., EFFECT OF RETINOIC ACID ON CONTRACTION OF COLLAGEN GEL INDUCED BY FIBROBLASTS, Biochemical and biophysical research communications, 205(1), 1994, pp. 455-459
Citations number
21
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
205
Issue
1
Year of publication
1994
Pages
455 - 459
Database
ISI
SICI code
0006-291X(1994)205:1<455:EORAOC>2.0.ZU;2-O
Abstract
Retinoic acid inhibited the contraction of collagen gel containing fib roblasts. Moreover, in its presence fibroblasts extensions were shorte r, fewer collagen fibers were recognized, cell adhesiveness was inhibi ted concentration-dependently, and microfilaments appeared to be disru pted resulting in morphological changes including loss of multipolar c ell processes due to changes in cytoskeletal linkages. (C) 1994 Academ ic Press, Inc.